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DNA methylation in this model is not a cause, but a consequence of repression and serves to fix the repressed state of the chromatin.
Underlying this, if you regard someone as a sexual outlaw, they'll start behaving like one; impudence and rebellion is a consequence of repression and intolerance".
In order to test whether lower levels of adipogenic differentiation markers in wt MEFs represent a direct consequence of repression by p53, p53 KO and wt MEFs were treated with Nutlin-3, a small molecule inhibitor of the murine double minute (MDM2) gene [43].
It may be that desmosome dissolution occurs simply as a secondary consequence of repression of E-cadherin.
Another IPA-retrieved report show however that transgenic mice with ectopic expression of DKK1 in intestinal crypts has an up-regulated p21WAF1/Cip1, possibly as a consequence of repression of c-myc expression [ 22].
Since the DNA damage response and DNA replication machineries share many components, we speculate that the downregulation of DNA repair genes during differentiation is a consequence of repression of cell cycle genes, particularly those involved in DNA replication.
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One story line demonstrates the punishing consequences of repression, the other the punishing consequences of liberation.
One of the most damaging consequences of repression was the near silencing of Argentina's truly cosmopolitan artistic conversation, a conversation that goes back decades.
It is a movie about the consequences of repression, both political and psychological, and the first half, which emphasizes a young girl's stunned alienation from the life — and the self — she had known, has a somber melodramatic potency.
Instead, eight years ago, Giacardy was writing her Masters thesis on the "Consequences of Repression on Foreign Sex Workers" and was permitted to ride along on the bus for six months to observe and help.
The international visibility of the philosophy of liberation was in part an unanticipated consequence of military repression in 1976 83 in Argentina.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com