In this section we draw together insights from previous work in three largely unconnected literatures, the literature on the healthy immigrant hypothesis, the literature on the assimilation of immigrants to the labor market of the host country, and the large and growing literature that examines the consequences of obesity on labor market outcomes.
Although it is well established that excessive consumption of a high fat diet (HFD) results in obesity, the consequences of obesity on development, maturation and remodeling of the skeletal system have not been well studied [1], [2].
It is well established that excessive consumption of a high fat diet (HFD) results in obesity; however, the consequences of obesity on postnatal skeletal development have not been well studied.
This emphasizes the importance of early detection and intervention directed at treatment of obesity to avert the long-term consequences of obesity on the development of cardiovascular diseases.
10 When we discuss the negative consequences of obesity on glucose and lipid regulation, inflammation, and body fat distribution, we must consider the role of physical inactivity in both development of obesity, and as an independent mediator of metabolic derangements.
Finally, we did examine data related to the three highest health care-related publicly-funded health-care expenditures in Canada and elsewhere (hospitalizations, physician visits, and medications), which represented a comprehensive estimate of the economic-consequences of obesity on Canada's publicly-funded health care system.
However, the consequence of obesity and metabolic disease on the function of skin resident lymphocyte populations and how this contributes to skin complications associated with obesity and metabolic disease are unknown.
Thus, it also appears logical that many pathways known to be modulated as a consequence of obesity may also impact on the expression of neuronatin.
Further support for this explanation comes from research on functional limitations as a consequence of obesity.
Future work should focus on strategies to identify those obese individuals most at risk of the negative metabolic consequences of obesity and on identifying other factors that contribute to metabolic status in obese individuals.
