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It was ruled that as a consequence of not observing the law, he involuntarily caused the death of Schnaufer.
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It is worth noting that this consequence of linkage is not observed for the case d = 0.15 with N = 10 (third column of graphs in Figure 1), suggesting that it depends on the linkage disequilibrium generated in the base population (see Table 1).
DOI: http://dx.doi.org/10.7554/eLife.05502.011 However, loss of Toll signaling also has consequences not observed by manipulating the BMP pathway.
It is tempting to speculate that at least some of the effects we observe here are consequence of not only histone acetylation, but of acetylation of Cdc6p as well.
In cryst_tetra, the crystallographic water positions are not observed, and this may be the consequence of not modeling the exact environment and packing of the crystal.
Though the extent of image degradation will interact with the size of the pupil, we did not observe functionally significant consequences of such variation perhaps because of the graded boundary despite considerable variability in pupil size.
Significant consequences to human health were not observed although more than 20% of the incidents resulted in fires.
However, cytoplasmic leakage of unspliced tra-2 mRNA was not a consequence of a general splicing defect, and was not observed upon depletion of other splicing factors.
This dual consequence of targeting CDK11 adds unique functionality not observed by targeting family members such as CDK1, CDK2, CDK4, or CDK6.
Remarkably, prelamin A is over-expressed under serum starvation conditions in hMSCs which already accumulate prelamin A. Although the molecular mechanism governing this effect is unknown, we suggest that this prelamin A "over-accumulation" could be the final consequence of the phenotypes that we do not observe under normal conditions.
Of note, we also did not observe cytosolic accumulation of MEF2D which has been reported as consequence of CMA blockage by knock-down of LAMP-2 expression [ 44].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com