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As a consequence of improvements in turbojet design, the turboprop less efficient at high speeds lost much of its importance in the 1960s, although it was retained for relatively short range aircraft.
This review highlights a number of areas where large potential benefits could be observed as a consequence of improvements made to the primary outcomes of the Building Blocks trial.
In the last decade European accidentology data have shown a significant reduction of the total number of fatalities, as a consequence of improvements achieved in the sector of car safety.
In 2008, as a consequence of improvements made to bicycling conditions within the city, the same magazine put Boston on its "Five for the Future" list as a "Future Best City" for biking, and Boston's bicycle commuting percentage increased from 1% in 2000 to 2.1% in 2009.
Brain metastasis is an increasingly common complication in breast cancer patients, possibly a consequence of improvements in systemic therapies.
Such inequity may be an unintended consequence of improvements in the organisation of care that are encouraged by pay for performance systems.
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Conclusion PEEP decrease during prone position as a consequence of improvement of oxygenation has a marginal but significant positive effect on cardiac index, related to an increase in global end-diastolic volume and probably venous return.
Another consequence of improvement of the dimensions "Reading and fine work" and "Adjustment" might be that item invariance across occasions can be assumed.
The available evidence suggests that the albuminuria-lowering effect of linagliptin may be due to inhibition of podocyte damage and myofibroblast transformation (36) as well as a consequence of improvement in renal inflammatory responses mediated by increased glucagon-like peptide-1 (GLP-1) activity (16, 36) or inhibition of tumor necrosis factor-α (16).
To the extent downstream consequences of improvement initiatives are often overlooked, there is danger in assuming that 100% adherence to guidelines will equate to improved patient outcomes so these outcomes must be measured.
Better understanding of this activity could also help us anticipate some of the unintended consequences of improvement processes, for instance, if tacit activities are not taken into account.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com