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The authors investigate the consequence of deleting the COM-1 protein that regulates conidial formation in Magnaporthe.
Hence, the consequence of deleting the 5 fill-in-the-blank items is to narrow the instruments' assessment of core EBP principles for many curricula.
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In this paper we describe the phenotypic and physiological consequences of deleting the AGE3 gene from the C. albicans genome.
Normally redundancy is considered between family members, however in the case of CSRNP-1 our studies clearly demonstrate that, if redundancy is the basis for lack of any consequences of deleting the genes on T cells, the redundancy must be with gene(s) unrelated to the CSRNP family of genes.
To understand the long-term consequences of deleting the genes encoding ADF and CFL1 for the animal, samples from the organs of sacrificed ADF−/− CFL1−/− mice 4 days after treatment with 4-OHT were taken for pathological examination.
An effective way to probe the physiological role of individual PKD isoforms is to look at the consequences of deleting the individual enzymes using gene-targeting strategies in mice.
In particular, we wished to confirm whether PFOR is responsible for pyruvate dissimilation, identify which of the many PFOR enzymes are most important, gain insight into the function of PFL and examine the physiological consequences of deleting these genes individually and in combination.
The yield with C. glutamicum doubled as consequence of deleting ldh and hdpA (Fig. 5).
As the reviewers point out, our model is distinct from the Kopan model in that tumour resistance is directly attributable to loss of epidermal barrier proteins, rather than to disturbed barrier function as a consequence of deleting Notch receptors.
Finally, by deleting smaller regions, we can be more confident that observed phenotypic effects are due to loss of lncRNA transcription, and not an unintended consequence of deleting overlapping genomic regulatory elements [ 13].
Thus, it will be interesting in the future to examine the consequences of deleting Rb in mice in which MYC activation is achieved using different systems, including different liver promoters and at different time points during tumorigenesis.
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