Consequences for loss of NEDD9 expression on E-cadherin expression or localization are not yet known.
The consequence for a loss at the final stages of the RWC is so tough to account for and those teams that know how to play tight tough and not pretty rugby do the best normally as England have shown by reaching the last two finals.
To determine the consequence for the loss of GATA6 in ovarian surface epithelia, we investigated the ovarian phenotype of GATA6 mice, since the homozygous mice are embryonic lethal [24], [25].
"It provides an explanation for a long-known consequence of loss of this enzyme," said Cantley, who is a stockholder and founder in Agios Pharmaceuticals, Petra Pharma Corp. and EPI Pharmaceuticals, which make drugs that target cancers and other diseases.
Saccharomyces cerevisiae provides an advantageous genetic system for studying the functional consequence of loss of a specific amino acid residue (a feat that cannot be readily accomplished in higher eukaryotes [3]), thus prompting us to carry out phenotypic analysis in budding yeast.
DOI: http://dx.doi.org/10.7554/eLife.06557.015 To determine the consequence of loss of Lpcat3 activity for hepatic gene expression we performed transcriptional profiling.
It seems that the non-significance of the p value at 12 months of treatment could be the consequence of loss of statistical power for comparison rather than of a decline in copper excretion between 10 and 12 months of treatment.
This ranking is based on the approach proposed by Wood and Gross (2008) which takes into account both biological risk (probability of loss) and four criteria for value (consequences of loss) including ecological specialization (non-exchangeability), value to ecosystems, evolutionary uniqueness (option value), and goods and services value to human society.
This called for testing the consequences of loss of N-AChE-S function on apoptosis.
Thus, despite the fact that Lpcat3 can catalyze the esterification of multiple unsaturated acyl chains into PC in vitro, and despite the fact that Lpcat3 is by far the most abundant Lpcat family member in the liver, the consequences of loss of Lpcat3 for PL composition were remarkably selective.
To assess the consequences of loss of local contacts for chromatin compaction, we measured the distance between two FISH probes (separated by ∼2.2 Mb one approximately 100 kb upstream of the TAD and the corresponding probe inside the TAD.
