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All patients in this study gave informed consent for collection and use of all the samples, which were collected in liquid nitrogen and stored at -80°C.
Adult males gave written informed consent for collection of blood as part of studies approved by the same committee.
Participants in this study initially gave broad written informed consent for collection and analysis of plasma and DNA for the Sanofi-Aventis CRESCENDO Genomic Substudy.
Signed informed consent for collection of the isolates was obtained from study participants of the PoPS study, which was also approved by the HREC.
All patients signed informed consent for collection of the biopsy prior to surgery.
Signed informed consent for collection of the isolates was obtained from the mothers.
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All men and half of the women and men were consented for collection of blood spots.
The authors wish to thank Catherine Murray and Sharon McPherson for patient recruitment, obtaining informed consent and for collection of tissue samples.
Informed consent for tissue collection was obtained from each patient and tissue collection was approved by the University Ethics Review Board.
All patients gave written, informed consent for the collection of tissue samples, and the local Research Ethics Committee approved collection.
All participants provided written consent for specimen collection and analysis under the study protocol approved by the Memorial Sloan-Kettering Cancer Center Institutional Review Board.
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