Sentence examples for consensus target from inspiring English sources
By studying modifications of the consensus target sequence, we show how different sequence elements contribute to the target recognition mechanism.
Alcoa also managed to narrowly edge the consensus target on revenue with its figure of $6.2 billion for the period and the Dow component said it expects worldwide aluminum consumption to be up 11% in the second half of the year.
Interestingly, this region contains no Pdx-1 consensus target sites, suggesting that the action of Pdx-1 may be indirect.
The CpHpH methylation analysis allowed us to infer that the consensus target sequence for de novo methylation was the −148 to −85 region of the 35Spro.
H2AX differs from its homologue H2A in that it contains a distinct C-terminal extension, with a consensus target sequence at serine 139 for the DSB-activated kinases ATM, ATR, and DNA-PK [4], [5].
The rigorous silencing phenomenon enabled us to analyze methylation in a number of the transgenic lines in parallel, which led to the discovery of a consensus target region for de novo methylation, which comprised an asymmetric cytosine (CpHpH; H is A, C or T) sequence.
To enhance our confidence, we only worked with consensus targets from the three public miRNA databases.
In a previous study, we have shown that ΔDNMT3B4 may preferentially target certain CpG enriched promoters (Wang et al., 2007) but no consensus targeting sequence was identified.
The glycine repeat domain at N-terminus is associated with consensus targeting for the endoplasmic reticulum, and rFKBP75 was predicted to be an ER membrane protein [ 40].
Consensus targets predicted by all three algorithms, showing significant upregulation in the miR-1 null vs wild-type hearts are presented as descending log2 fold change in miR-1 null over wild-type hearts (lower).
The 2015 NHS England consensus statement on JIA treatment includes a statement on the goals of therapy [ 18 ▪] (see below), but evidence-based consensus targets, including targets for remission induction, maintenance therapy and guidelines on drug withdrawal, are not yet uniformly defined in JIA [ 17].
