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Wissel J, Ward A, Erztgaard P, Bensmail D, Hecht M, Lejeune T, et al. European consensus table on the use of botulinum toxin type A in adult spasticity.
Fig. 2 Reader consensus table for the 92 analyzed SISCOM images.
Eleven statements did not reach consensus (Table 2).
Both raters resolved all discrepancies and achieved consensus (table 2).
Taxonomic treatments lack consensus (Table 1) and phylogenetic work has only recently been attempted.
Fifty-two items were rated essential with strong consensus (table 1); 54 items were rated essential with good consensus (table 2); 25 items were very important with good consensus (table 3).; 12 items were rated very important with weak consensus; 4 items were rated important with good consensus; 2 items were rated important with weak consensus; 1 item was rated not important with weak consensus.
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In the specific case of Taiwan, several cases have been reported as being locally derived (as outlined in the evidence consensus tables in the Dryad dataset) and therefore the evidence consensus scores Taiwan as likely to have the disease present.
For comparison, we re-examined data from 4 additional chronic-infection subjects previously studied by 454 sequencing of the V3 region [25], finding a similar pattern in positions where patient-consensus differed from subtype-consensus (Table S8).
The analysis of the validated intron sequences revealed the presence of many conserved bases compared with the well-known consensus sequence (Table 4 and Supplementary Table S3).
One striking observation, however, was the high frequency (51%) of interacting proteins that did not possess a classical C-terminal consensus sequence (Table 1; Additional file 3: Supplemental Table S6).
For item development, LTB brought together an international expert consensus group (Table 1), with the technical support of WHO.
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