The South East Asia Infectious Disease Clinical Research Network convened subject matter experts at a workshop to make consensus recommendations for study design of a clinical trial for use of intravenous immunoglobulin (IVIg) in severe hand, foot and mouth disease (HFMD).
On March 4 5 , 2014 in Bangkok, Thailand, the South East Asia Infectious Disease Clinical Research Network SEAICRNN) convened subject matter experts at a workshop to make consensus recommendations for study design of a clinical trial for use of intravenous immunoglobulin (IVIg) in severe HFMD.
Previous studies 14 16 have set a Cronbach's α of ≥0.8 as representative of an acceptable measure of internal reliability and this, therefore, will be the priori definition of consensus for this study.
However, there was expert consensus for our study in 2011 that all of the elements included in our score were at least, on average, more likely than not to be included in a high-quality ICU analgesia, sedation and delirium order set.
The use of few non-B subtypes in those analyses may explain the high conservation of PR and RT enzymes as the standard consensus for resistance studies is the subtype B. In our study, we found that one third of RT C-terminal sites are highly conserved, independent of HIV-1 group M subtypes or treatment status.
Disease severity and internal organ involvement was assessed according to the recently published consensus for SSc studies [ 25].
However, to our knowledge, there is no systematic review focusing on injurious falls methodology in fall prevention trials aiming to develop a methodological consensus for future studies.
All brain imaging data were obtained on a 1.5 Tesla GE Signa (Milwaukee, WI, USA) system in compliance with consensus recommendations for studies examining vascular cognitive impairment [ 19].
Two reviewers (JE and JG) assessed study quality and reached a consensus for each included study.
There is no final agreement about the terms and therefore a discussion in study teams and Institutional Research Boards (IRBs) may lead to a different consensus for each individual study.
