However, there is no evidence-based consensus for a threshold of AS that will distinguish demented from non-demented people [ 5, 14, 15].
Although there is no consensus on a threshold for good value for resources expended, we present our results in the context of commonly cited thresholds of incremental cost per QALY of $50,000 or $100,000 [ 21]].
While there is no consensus on a threshold cost-effectiveness ratio under which an intervention is cost-effective, a useful proxy suggested by WHO to compare different public health interventions is per capita GDP [ 38].
The group was unable to achieve consensus on a threshold dose of vasoactive medications below which it was acceptable to mobilize patients, the rate of change in dose and criteria for impaired perfusion and shock.
Due to the fact that there is no fixed value and to the lack of consensus in Spain, a threshold of €50,000 per QALY gained, for end-of-life drugs, was used according to the UK National Institute for Health and Clinical Excellence [18, 19].
We define a consensus prediction by a threshold of 0.5: if the presence fraction is greater than 0.5 the gene is present, and vice versa.
Bootstrap resampling was carried out 100 times on each alignment and the results were summarised with the majority-rule consensus method with a threshold of 70%.
Because of the lack of a consensus threshold for defining an abnormal systolic blood pressure (SBP) response, this was analyzed as a continuous variable.
In Figure 1A, a consensus threshold value of 0.35 (default value) was used.
From the four samples, we predicted 2753 functions using a consensus threshold of three (see Additional file 9).
