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Information on benzodiazepine prescriptions among 5,200 patients from 16 consecutive trimesters between 2007 and 2010 was available for analysis.
In 58 women (12, 22 and 24 in the consecutive trimesters), the results of CGMS were analysed for a 7 day period before blood collection for 1,5-AG and HbA1c measurement.
42.3% of these women were dispensed an SSRI in each trimester, 75.4% of the women were dispensed an SSRI in consecutive trimesters and 97.6% of the women used the same SSRI throughout the first trimester without switching.
In a previous study of SSRI dispensing patterns, we found 75.4% of the women were dispensed an SSRI in at least two consecutive trimesters, indicating that the women were using the SSRIs [ 39].
75.4% of the women were dispensed an SSRI in at least two consecutive trimesters, from T0 to T3,[ 13] and this would indicate the women are using the SSRIs as each dispensing costs from $A3.60 to $A4.60 per medicine for concessional patients and from $A22.40 to $A28.60 for general patients, during the period of the study.
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RPL was defined as women with 3 consecutive first trimester miscarriages or 2 second trimester miscarriages.
Materials and methods: All pregnant women presented with first-trimester inevitable miscarriage with a history of RM, defined as three or more spontaneous consecutive first-trimester miscarriages before 12 weeks' gestation, were included in the study (RM group).
The current study included women with a history of two or more consecutive first trimester miscarriages, depending on the definition used by the American College of Obstetrics and Gynecology [ 2] rather than the definition of three or more miscarriages [ 6], which is used traditionally to define RM.
Passive samplers were carried for seven consecutive days during the second trimester of pregnancy [ 7].
Exposure had been assessed using active air samplers carried by the woman for two consecutive days during the second trimester of pregnancy.
We used a prospective design to invite a cohort of pregnant women to participate in the three consecutive surveys: the second, third trimester of the pregnancy and 1 2 days after childbirth.
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