Distinctive features of registration trials in oncology need to be considered when these studies form basis for EBA, especially in cancer-indications with long post-progression survival; and with several consecutive therapeutic options available post-progression.
To achieve an intuitively accessible appearance of test contents, layout directives were chosen so that for example page breaks should not disrupt the consecutive answer options of a common MCQ.
So they're committed to him for at least two more years; after that, the contract essentially features three consecutive one-year options.
For now, the newspaper — located downtown since its founding as the Los Angeles Daily Times in 1881 — has a lease until 2018, with two consecutive five-year options beyond that, a person familiar with the terms said in June.
For a proxy variable or vitamin D, we asked how much time was spent outside between two consecutive night shifts (options varying from <10 min to >1 h).
The medication was applied twice daily (morning and evening at bedtime) for 10 consecutive days, with the option to prolong treatment to 14 days, until resolution of all signs and symptoms, or study end.
Here we report an experience of multidisciplinary management and selection of tailored multimodality treatment options of consecutive HCC patients in clinical practice, according to defined clinical criteria.
Mr. Kumar, 41, received a salary of $1 million for a second consecutive year, and stock options valued at $13.3 million, the company said in its proxy statement filed with the Securities and Exchange Commission.
A retrospective review was performed of all consecutive patients without surgical options for revascularization who underwent a percutaneous vascular intervention of the tibial arteries between 1 August 2006 and 31 December 2008.
Each treatment protocol consisted of twice-a-day (morning and evening) application of one of the treatment options for 5 consecutive days, followed by 2 days of nontreatment.
