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Briefly, periods of five consecutive alterations in inspiratory/expiratory ratio (1 2 1.5 1) were applied by the ventilator.
Briefly, the inspiratory pause was varied to introduce 5 consecutive alterations in inspiratory/expiratory ratio (1 2 to 1.5 1) to the normal mechanical ventilation.
Lung volume was assessed in anaesthetized mechanically ventilated rabbits successively by measuring i) ELV by analyzing CO2 elimination traces during the application of periods of 5 consecutive alterations in inspiratory/expiratory ratio (1 2 to 1.5 1), ii) measuring EELVMBW,He by using helium as a tracer gas, and iii) EELVCT from CT scan images by computing the normalized lung density.
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Released proinflammatory endothelial cytokines may themselves also contribute to the production of MPs [ 44], thereby amplifying the inflammatory response and the consecutive alteration of the vascular function [ 45].
PE is associated with abnormal placentation consecutive to alterations in the vascular remodeling of uteroplacental arteries mainly due to abnormal invasion of trophoblasts and unconverted narrow spiral arteries [2].
These nature selected mechanisms for survival result from random events presented in the final consecutive genetic alterations.
In principle, epigenetic changes occurring during embryonic development will have a much greater impact on the overall epigenetic status of the organism because, as they can be transmitted over consecutive mitotic divisions, alterations occurring in single embryonic stem cells will affect many more cells than those occurring in adult stem and/or somatic cells during postnatal development [ 147].
Cancer arises from the consecutive acquisition of genetic alterations.
Cancer arises from the consecutive acquisition of genetic alterations that, in general, can be recognized as the combination of the loss of function or transcriptional down-regulation of particular genes (tumor suppressor genes) and the activation or transcriptional up-regulation of other genes (oncogenes) [ 3].
Tags that are undetectable in a consecutive pattern may indicate structural alterations.
They reported several clusters of genes with concerted alterations over the consecutive Braak stages and their possible involvement in AD pathogenesis.
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