Sentence examples for consecutive activation from inspiring English sources
Nor did this study address the consecutive activation of TAK1/mitogen-activated protein kinase kinase (MEK /protein kinase B (AKT /NFκB and SMAD pathways upon TGF-β stimulation as Gingery et al. [ 55] did in osteoclasts.
Thus, Scenario 3 is characterized by a consecutive activation of functional modes remaining active during a period substantially larger than the time scale of the relevant functional process (here the finger movement).
Both signaling pathways are activated by numerous growth factor receptors and mediate intracellular signals by the consecutive activation of downstream proteins.
A maximum activity was achieved when the secondary amine with the same primary alcohol-containing substituent was surrounded by surface silanols, indicating the potential advantage of simultaneously activating both reactants by the formation of a hydrogen bond in contrast to the consecutive activation when there is only one promoting site in the vicinity of the amine.
Programmed cell death or apoptosis in eukaryotes is executed by the consecutive activation of specific biochemical pathways that produce a dying cell, with typical morphology, such as cell shrinkage, membrane blebbing, chromatin condensation, as well as distinct DNA fragmentation [5].
In run A4, two consecutive activation steps with glutaraldehyde were assessed.
Vause and colleagues showed that incubation of cultured trigeminal ganglions with CO2 or capsaicin resulted in an acidification of culture medium and a consecutive nociceptive activation with CGRP release [13].
Thus, the results suggest that lysosomal or proteosomal degradation of LAPTM5, whose impairment might enhance the accumulation of the protein and/or LAPTM5-positve vesicles, in addition to the consecutive transcriptional activation of LAPTM5 by cellular stress, also plays a critical role in degeneration and cell death in NB cells.
Secondly, pharmacologically induced consecutive PKA and PKC activation provides potent cardioprotection.
Consecutive RAF1 activation has been reported to induce glioma formation in mice [ 93].
Pharmacologically induced consecutive PKA/PKC activation mimics TP and induces extremely potent cardioprotection.
