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Specifically, a functional connectivity study compared the functional connections of left anterolateral superior temporal cortex during narrative speech comprehension in normal subjects and in a group of patients with chronic aphasic stroke (Warren et al., 2009).
In addition, a functional connectivity study [ 22] has revealed the aberrant functional connection between amygdala and the prefrontal cortex, suggesting neural correlates for emotion regulation deficits in adults with GAD.
The connectivity study showed no overlap between the number of effective connections or edges in vegetative state patients and in controls.
The connectivity study by Parvizi et al. [19] showed a similar pattern of connections with frontal and cingulate structures involved in execution or planning of actions.
Furthermore, a recent task base functional connectivity study in humans suggested that ACC might act as a high-level motor control region11.
An effective connectivity study was carried out on 16 young, healthy subjects performing an alertness task.
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Moreover, functional connectivity studies disclose not only direct (anatomical) connections, but additional connectivity patterns which are mediated by other brain structures.
This will require functional connectivity studies that distinguish forward and backward connections (e.g., dynamic causal modeling).
Assuming that network connections are reflected in the patterns of electrical activity, connectivity studies often entail simultaneous measurement of activity in a large number of neurons.
In particular, anesthesia is a highly relevant confounder, which needs to be adequately controlled for in functional connectivity studies.
Costa, A., Petrenko, A. A., Guizien, K. & Doglioli, A. M. On the calculation of betweenness centrality in marine connectivity studies using transfer probabilities.
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