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It can be seen that the highest connectivity TFs varied from one functional group to another - STAT3 had 39 connections in Development, p53 had 26 connections in DNA Damage, (iii) c-Jun had 12 connections in Apoptosis and Survival, (iv) GATA-1 had 5 connections in Cytoskeleton Remodeling, and (v) c-Myc had 2 connections in Cell Adhesion.
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Speculatively, however, the preponderance of testosterone receptors in male brains may be the basis for differences in thalamo-cortical connections: early in development axonal growth towards the cortex is in part guided by projections from cortex to the thalamus [ 17]; and these could be affected by variations in gonadal hormones.
Although from an anatomical perspective, spur formation in the Achilles tendon and the plantar fascia could possibly be related to the transfer of mechanical stress from site to site, the connection in the development between these spurs and their prevalence for age and sex remain uncertain.
The Montauk Project connection was lost in development, but the final version of Stranger Things still seems to share a few tenuous similarities with Kessler's original short film, like disappearing kids and buggy technology and some freaky-ass shit in the sky, but those tropes aren't exactly unique to the Montauk short to begin with.
Together, these micro- and macroscopic features have been used in numerous studies of brain connections in diseases, 91 development, 39 aging, 92 and a number of different behaviors such as visuospatial attention, 93 language, 94 cognitive control, 95 and skill learning.
As more cell type-specific promoters are identified for neurons in the cerebellum, application of these tools will help elucidate the roles of different transient connections in cerebellar circuit development, and may help us understand if these transient developmental features are interrelated or work synergistically.
Circuit rewiring is energetically costly, which argues that transient connections may be pivotal in development.
Included in the government's strategy is public investment in full fiber for rural areas; and new legislation to guarantee full fiber connections in new build developments; as well as a series of regulatory reforms intended to drive investment and competition — which it says will be tailored to different local market conditions.
A top Treasury Department official then sent an e-mail message to staff members that called it a "major screw-up" for the ambassador to explicitly acknowledge a connection between the holdup in development loans and American political concerns in Haiti.
Furthermore, children have more short-range connections which are progressively replaced by longer range connections in adulthood, suggesting that development is characterised by both progressive integration and segregation [ 36, 37].
Conversely, might there be a role for connections between closely spaced SACs early in development?
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