Furthermore, patients showed an overall decrease of both inter- and intra- hemispherical structural connections (tracts), Figure 2. Finally, the 3D-graph visualization showed that the structural loss was global and asymmetric, Figure 3. Figure 1 Group difference Connectrogram.
These data, assessed with a qualitative high-resolution diffusion tractography, reflect our probabilistic tractography findings by establishing that the two subregions of the FPC have differential white matter connectivity, and provide detailed evidence that both local, short fibre connections and long association tracts contribute to the structural heterogeneity of the FPC.
This prediction was based on the distinct structural connections these tracts establish with the HC and vATL, and generated from published theoretical/computational accounts of representational models (Cowell et al., 2010; Elfman et al., 2014).
In addition to long-distance connections, intermodule connections, or fiber tracts linking different modules are also important to keep the community structure of brain networks and these also provide shortcuts for communicating with other functional or structural modules.
Different imaging modalities allow the mapping of structural connections (axonal fibre tracts) as well as functional connections (correlations in time series), and individual variations in these connections may be related to individual variations in behaviour and cognition.
The implementation of a copper connection with simple tracts of cable between contiguous storeys could provide an easier scalability of the structure, simple maintenance of the backbone, lower costs because of cheaper connectors, safer integration and transportation.
The connections of these tracts are consistent with our finding that the lateral cluster is structurally and functionally connected to lateral brain regions, and that the medial cluster is structurally and functionally connected to subcortical and medial brain regions.
Rather than discussing all the issues raised by their paper, we summarized the areas of agreement and the major difference: Schnakenburg et al. were unable to analyze ovulation whereas we discovered this connection between reproductive tract secretion, Hr39 expression, and ovulation.
To further investigate the local asymmetries of the structural connections, we then reconstructed several major white matter tracts connecting different brain regions.
Although it is clear that PTB has a preference for binding to pyrimidine tracts, the connection between PTB binding and inhibition remains elusive.
