Porosity includes both connected porosity and unconnected porosity.
The relationship between the connected porosity and the total porosity is subparallel to the isoline (total porosity = connected porosity), whereas the vertical deviation from the isoline is given by the isolated porosity.
[12] The total and connected porosities decrease during sintering whereas isolated porosity increases.
The isolated porosity was estimated from the difference between the total and connected porosities.
Arbitrary connections for intra-porosity flow and inter-porosity flow are incorporated into the design to allow for the convenient transformation between Multi-Porosity and Multi-Permeability formulations.
While interconnectivity through larger connections improved with higher porosity, compressive mechanical properties of scaffolds declined at the same time.
We demonstrate that the intra-porosity connections in the inorganic and organic matrix have negligible impact on the global gas flux, while the inter-porosity connections have different levels of importance for the gas production.
Therefore, providing a bone-mimetic scaffold is another crucial factor for bone tissue engineering in addition to the biocompatibility, 3D architecture with high porosity, and interpored connection.
It is concluded that providing a bone-mimetic scaffold is another crucial factor for BTE except the biocompatible, 3D architecture with high porosity, and interpored connection.
Although the optimal scaffold for BTE is not discovered yet, several characters are required including biocompatibility, biodegradability, three-dimensional architecture, high porosity, and interpored connection.
