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However, the connection of pain with functioning across domains of HRQOL in SCD is not firmly established.
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However, the cause - effect connection of sleep, pain and autonomic dysfunction in FM needs further characterization.
A very different response to this time of radical change came from Donatien-Alphonse-François, comte de Sade, generally known as the Marquis de Sade, whose fascination with the connections of power, pain, and pleasure, between individuals and in society's larger structures, gave rise to the word sadism.
My strong connection to the implications of pain — both its presence and absence — is no doubt why the Blockers' story touched me so deeply.
There had been no traumas in connection to the onset of pain.
By text mining, only one of the 63-set miRNAs has a published connection with pain, while many of the putative target transcripts (a set of 153 genes that contain 3 or more 63-set target sites and are significant mRNA change in L4 DRG) are associated with neuronal remodeling, a result that reinforces the results of pathway analysis.
Increased understanding of the body-mind connection in pain and the importance of relaxation, breathing and positivity for pain management.
There is a great need to educate the public toward a greater understanding of the connection between pain and their reactions toward the symptoms.
However, regarding the latency period between initial trauma and appearance of pain, we consider a connection to be unlikely.
Analogous to mathematical chaos theory these connections create a vicious circle (positive feedback, iteration) of pain [ 20].
Its specific novelty is a connection between pain perception via activation of TRPV1 sensory neurons to activation in the anterior cingulate cortex on the one hand, and a local epinephrine/norepinephrine-dependent induction of CX3CL1/CX3CR1 in the L5 spinal cord on the other.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com