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In the case of the breast carcinoma cell lines MCF-7_wt/_ADR, the methylation status of CGIs associated with the genes ABCB1, BRCA1, CDH1, DNAJC15, ESR1, GSTP1, PLAU, SULF2 and TGM2 was connected to the expression of the genes.
In case of the ovarian carcinoma cell lines OVCAR-5, OVCAR-4 and NCI/ADR-RES, the methylation status of CGIs associated with the genes ABCB1, BRCA1, CDH1, DNAJC15, and SULF2 was connected to the expression of the genes.
Lastly, genetic factors could also be connected to the expression of different immune patterns among patients with similar types of infection and sepsis severity [ 12].
Vectoring the bacterial antibiotics towards their disease targets should be closely connected to the expression of adequate grooming and weeding behaviors known to be important for the successful control of Escovopsis infections [ 48].
Since we only analysed a 10 kb region around the transcription start site of each gene, we can not exclude that DM in other, more distant regulatory regions may be more closely connected to the expression level.
The finding that CFTR, although detectable in RT-PCR, cannot be activated in trp4-defiecint mouse aorta endothelium might be of a special interest, since it shows that the functional activity of CFTR may be connected to the expression of trp4, a member of the trp-family that is involved in capacitative Ca2+ (CCE).
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P: I think people now are pretty connected to the overall expression and much less the style.
The remaining helix, P1, includes both the 5′- and 3′-ends of the aptamer domain and is directly connected to the downstream expression platform.
The gedunin and celastrol profiles were strongly connected to the gene expression profiles of multiple, structurally distinct HSP90 inhibitors leading to the hypothesis that these agents were themselves HSP90 inhibitors.
When AR was knocked down, the amount of AR protein was reduced (lower panel, lanes 3 and 4), coupled with a decreased growth rate of LNCaP cells overexpressing BCAS2, and of the GFP control cells (upper panel), indicating that the increased growth rate associated with BCAS2 may be connected to the increased expression of AR.
The non-random arrangement of genes in the genome is intimately connected to the pattern of gene expression across the genome [ 1].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com