For example, considering a small network with 3 GOBP terms, GOBP 1, GOBP 2 and GOBP 3, and a pathway P, where GOBP 1 and GOBP 2 were connected, GOPB 3 was not connected with GOBP 1 and GOBP 2, and all GOBP terms were connected to pathway P.
In particular, the genes within pathways often behave in a coherent manner, connected to other pathways through a consistent set of positive or negative interactions.
Finally, the pathway maps that provide the necessary compounds for the conserved pathway maps are connected to the pathway-map network, until there are no more suitable pathway maps to be added.
Each pathway is a node in the network and is connected to other pathways according to the links in the KEGG diagram.
More specifically, we are interested in pathways that are acquired or lost, those evolving to be more (or less) connected to other pathways in the cell, and finally those evolving to be more (or less) centrally located in the NIPs.
Thus, the pathways related to FA biosynthesis and elongations were extracted from the genome-wide metabolic network directly connected to these pathways to compare the different network structures of the four seeds.
Some of the mutated genes were somehow connected to the pathways followed by Sonic hedgehog, an extremely important growth-promoting protein involved in embryonic development.
However, Src and Abl are, like mTOR and AKT, broadly connected to signaling pathways for many cellular functions, and whether Src, ErbB2/3, mTOR, AKT, and PI3Kγ actually form a mechanistic network in U87 mg electrotaxis requires further confirmation.
Because the function of hydrogenases is intricately connected to metabolic pathways, the pH-dependence of H2 consumption must be measured in vivo.
Lymph nodes are connected to lymphatic pathways and blood vessels.
