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For example, we observe a highly connected module comprising a range of fast muscle structural subunits (MYH1, TNNT3, MYOM2, MYBPC2, TMOD4, ACTN3 and TPM1), along with the glycolytic enzymatic machinery.
To further demonstrate this, we took the most highly connected module for each tissue.
These genes formed a tightly connected module with an average of 3 ± 1 interactions/gene (figure 4).
Hierarchical organization is particularly evident with leucine catabolism, which forms a functionally coherent and tightly connected module, nested within a supermodule [see Fig. 8 and Additional file 3].
Ribosome network is formed by a single highly connected module in both, human and yeast, and both networks present low evolutionary plasticity in their components.
The most highly connected module in the PAG was the midnight blue module (330 genes) containing 145 direct protein interactions (Fig. 6a).
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In these cases, large and densely connected regions are relatively rare, whereas small, densely connected modules are more frequently found.
A photovoltaic field is classically made of parallel connected strings, each one formed by a number of series connected modules.
For example, seed-and-extend methods use connection density and neighboring network information to find heavily connected modules in PPI networks.
Large, densely connected regions of such networks are therefore quite few; instead, small, densely connected modules are more frequently found.
The mc-Si test bed was of 1.6 kWp capacity, comprising 10 series connected modules, each of 160 Wp.
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