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Here we describe a different polymer conjugation technique, conjugating the ALN to the monomer prior to copolymerization, thus controlling the drug loading and enabling higher loading percentage of ALN (7% mol) on the polymeric backbone.
Both surfaces of QNP and SiNW arrays were functionalized by a high affinity biotin-STR conjugation technique.
The conjugation technique used may be used to create OXM derivatives and other related hormones to obtain long-lasting variants, with improved suitability for clinical use.
This review details recent advances in the design of synthetic vaccines using NKT-cell agonist as adjuvant, highlighting the role of organic synthesis and conjugation technique to enhance the immunological actives and to simplify the vaccine constructs.
We used this surface-functionalized method on nanotopographic substrates to separate targeting specific cells (e.g., CD4 T cells) among different kinds of cells via the novel STR-biotin conjugation technique to capture the incoming targeting cells in PBS solution as we have developed previously [20, 21].
To avoid these difficulties, an ideal site-directed conjugation technique would use residues natural to the protein that are revealed for modification only under defined conditions.
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Although a wide variety of anticancer agents including some toxins have been the subject of conjugation techniques, in this review, low molecular weight cytotoxic drugs conjugated covalently to the carriers are considered.
Significant improvements in QD synthesis, coating, and conjugation techniques combined with their photostability and brightness have made QDs invaluable tools for in vivo imaging.
Amine groups were chosen to couple targeting units by using two different conjugation techniques, one involving glutaraldehyde as a cross-linker and other method involved MBS modification of NPs.
This synthetic approach uniquely allows for the direct fabrication of biologically functionalized gel scaffolds with ideal structures for adipose tissue engineering, which provides a competitive alternative to conventional conjugation techniques such as copper mediated click chemistry.
The coupling of p18-4 to liposomes was carried out through conventional, post insertion and post conjugation techniques and prepared liposomes were characterized for their size and level of peptide modification.
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