Sentence examples for conjugation of active from inspiring English sources

Alternatively, conjugation of active targeting ligands that exhibit high affinities to cancer receptors is also a widely used strategy to increase tumor-targeting efficiencies of the NPs.

Two surface chemistries, PEGylation and conjugation of active targeting ligands such as cyclic Arg-Gly-Asp (c-RGD) peptides, have been widely applied to enhance the delivery of NPs into tumor sites.

Given that, micro-patterning techniques have profited by combining micro-fabrication technology with the chemical conjugation of biologically active molecules to provide new culture systems where cells can be cultured within a specific geometry.

Further studies involving conjugation of an active therapeutic to the substrate are necessary to validate the system.

These results will be especially valuable in monitoring and controlling the conjugation of biologically active molecules to NC surfaces for improved bioassays.

The distribution effect was applied to separate CdSe/ZnS NCs encapsulated in silica, as well as surface-modified with DNA, which allows the estimation of the yield of conjugation of biologically active molecules to a particle surface.

This method is simple and easy to design without direct conjugation of redox-active element.

We demonstrate the enhanced activity of these particles over free drug and show further improvement of their delivery through conjugation to active cell-targeting antibodies toward death receptor 5 (DR5).

The latter facilitate metabolization and conjugation of the highly active transformed organic compounds, ultimately leading to their elimination from the organism (Köhle and Bock 2007).

Increasing the hydrodynamic radius by chemical conjugation of the pharmacologically active peptide or protein to repeat chemical moieties, e.g., to PEG (PEGylation [ 1, 2, 11, 12 ]) or hyaluronic acid [ 31 ].

Considering the growing importance of the biocompatible scaffolds in the recent tailored tissue engineering technique, these results indicate that the present strategy of 2-iminothiolane-based conjugation of polysaccharides with biologically active peptides will become a key and potential technology to develop desirable scaffold materials for the tissue regenerations.