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The low interaction energy of Arg conjugate based on molecular modeling may contribute to its enhanced cytotoxicity.
We report on the synthesis and properties of a new multimodal theranostic conjugate based on an anti-cancer fluorinated nucleotide conjugated with a biotinylated dual-labeled albumin.
Therefore, the triblock HPMA copolymer DOX conjugate based nanoparticle is promising as a potential drug delivery vehicle for breast cancer therapy.
A new self-immolative spacer conjugate based on a chemical adaptor unit aiming at controlled releasing drugs was designed and synthesized.
In this study, we designed, prepared and characterized biodegradable amphiphilic triblock HPMA copolymer doxorubicin (copolymer DOX) conjugate based nanoparticle as enzyme-sensitive drug delivery vehicle.
The anti-TPO Liaison XL 2-step assay was a sandwich CLIA that used directly coated magnetic microparticles with recombinant TPO as solid phase and a conjugate based on an isoluminol derivate.
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Thus, peptide conjugates based on tris(hydroxypyridinones) are conducive to translation to kit-based preparation of PET tracers, enabling the expansion and adoption of 68Ga PET in hospitals and imaging centres without the need for costly automated synthesis modules.
Open image in new window Fig. 2 Schematic for gold NP oligonucleotide conjugates based detection system.
Here, we report a significantly improved synthetic procedure for the preparation of the conjugates, based on the protection of the daunosamine moiety by N-trifluoroacetylation.
A versatile bifunctional biphenyl-azo conjugated based aldoxime (DOXPA) was developed and its photo-responsive behaviours upon the addition of analytes has been investigated using UV vis absorption, fluorescence emission, quantum yield and fluorescence lifetime measurements.
They prepared a library of DOTA and DTPA peptide conjugates based on the C-terminal structure of minigastrin.
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