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Patients were then followed up for a period of at least 8 weeks from the time of conjugate administration.
The low concentrations of N-retinylamides found in the liver after conjugate administration are advantageous for minimizing potential toxic side effects associated with the drug.
In contrast, liver concentrations of N-retinylamides in mice treated with PEG-GFL-NH-Ret were below the detection limit in the first 4 h after conjugate administration and then were maintained at a stable low level from 8to7272 h thereafter.
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Three dogs were concurrently treated with intravenous infusion of D-FITC (140 mg per animal, ∼5 mg/kg) and intracisterna magna (ICM, "into the brain") injection of D-Cy5 (5 mg per animal, 0.17 mg/kg) and euthanized 48 h post-conjugate administration.
A single MenC conjugate vaccine administration above 5 years of age seems to induce persistent protective SBA antibody levels, gradually increasing with age of vaccination.
A 1999 study [ 20] reported a median parental WTP of $10 to $25 to reduce an infant's pain and emotional distress from childhood vaccination, while a study in 2001 reported a WTP of $25 to prevent fever and fussiness in young children after pneumococcal conjugate vaccine administration [ 25].
In vivo imaging of QDots-HA conjugates after oral administration was analyzed to investigate their biodistribution in nude mice.
To determine whether pneumococcal carriage at the time of 11-valent pneumococcal conjugate vaccine (PCV-11) administration interferes with immune response in infants.
The optimum schedule of administration of conjugate vaccines is not yet well defined.
Also, the targeting system, although giving high tumour to blood ratios of antibody-enzyme conjugate (10 000 : 1) required administration of a clearing antibody in addition to the antibody-enzyme conjugate.
Cytotoxic profiling (MTT assay) showed that conjugates were safe for administration in the concentration range of 2 10 mM up to 24 h.
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CEO of Professional Science Editing for Scientists @ prosciediting.com