Furthermore, the dominant-negative phenotype induced by mutation of the predicted EF hand motif in the Sec62 protein, which was completely congruent with the effects of Sec62 depletion or treatment with calmodulin antagonists, strongly points to a direct regulation of Sec62 function by Ca2+ binding to the motif.
In the aggregate, these data are congruent with the positive effect of glutamine on insulin sensitivity.
Except for rhodamine B, all of the tested compounds caused a decrease in the stimulated Abcb4 ATPase activity and the results are congruent with the sensitizing effects of cyclosporin A and PSC833 in the embryotoxicity tests and with the effects of cyclosporine A, PSC833, MK571, vinblastine, tonalide, galaxolide and phenanthrene on rhodamine B accumulation in embryo tissue.
In addition to biological plausibility as described above, our results are congruent with the known effects of pharmacologic agents, such as hormone therapy or estrogen antagonists.
This result is congruent with the absence of a strong founder effect during domestication and with similar amounts of genetic divergence occurring between wild and domestic pigs as has been observed between various European wild boar populations [ 37].
When the packaging design is congruent with both patterns, the effect is amplified and the scanpath of most of the users is predictable.
The effect size was congruent with the p-value in the present study.
Finally, the observed AC cluster effect is congruent with the role of ACs in planning and implementing screening policy.
We also found a stronger genetic founder effect in smaller islands, congruent with the patterns of species diversity (Figs 2 and 3), in agreement with the species-area effect as predicted by island theory (MacArthur and Wilson 1967; Triantis et al. 2012).
Although these examples are congruent with the hypothesis that traits underlying component Allee effect are subject to adaptive evolution, they are not strong evidence.
