Exact(3)
Mutations in the Aspm gene at the MCPH5 locus are the most common cause of human primary microcephaly leading to a reduction of cerebral cortex size, congenital failure and mental retardation (Bond et al., 2002, 2003).
Using calcium imaging, we found that fewer neurons had matured and less synchronized neuronal activities had been detected at the late stage of development in the Aspm mutants (Fig. 5), which could be the reason that ASPM-related microcephaly patients present congenital failure and mental retardation (Bond et al., 2002, 2003; Shen et al., 2005).
In humans, the congenital failure in the function of the GnRH neuroendocrine system results in reproductive disorders termed hypogonadotropic hypogonadism (HH), and these patients can also show a wide variety of non-reproductive phenotypes.
Similar(57)
Proportionate congenital growth failure due to GH deficiency is a predominant type of isolated deficiency.
The cause was congenital heart failure, said his sister Shami, an actress who performed in some of his productions and who was with him when he died.
The authorities claimed the body of his wife, who had died of congenital heart failure, for examination.
Try telling that to the mother of a blind childwith congenital heart failure whose mental age will forever be 6 months.Parents of children with severe disabilities must provide round-the-clock supervision and care.Then there's theenormous cost of specialized medical equipment and supplies, and the heartache of constant medical crises and setbacks.
"I think 9/11 and the loss of a child were probably the two most difficult things in my life," said Pitino, who lost an infant son to congenital heart failure in 1987 and his brother-in-law, Billy Minardi, in the 2001 World Trade Center attacks.
The first person to have the surgery was Michelle Gribilas, 57, who was suffering from congenital heart failure.
Like many dogs that haven't received proper veterinary care, Cora-Bella arrived at the rescue with numerous health issues, including congenital heart failure and skin issues, among other concerns.
On 21 July 2012, he died at his Coronado, California, home of congenital heart failure, and was buried at Fort Rosecrans National Cemetery in San Diego.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com