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They face formidable obstacles.
Both proposals, like the commuter tax, face formidable obstacles.
But Mr. Chen's lawyers face formidable obstacles.
Factors affecting HIV-1 latency present formidable obstacles for therapeutic intervention.
Antiretrovirals face formidable obstacles for wide-scale prevention of HIV infection.
Trump continues to face formidable obstacles to winning.
But they face formidable obstacles for dealing with pandemic threats.
All of these present formidable obstacles to the development of novel therapeutic approaches to AD.
Others confronted formidable financial problems.
And the sting came in the tail, with a reminder for the Livingstone camp of the formidable obstacles in confronting the Tory challenger's star quality: for a long period at the end of the event, he was mobbed by people wanting to shake his hand, take his picture on their mobile phones and get his autograph.
However, the Rhinos present a formidable obstacle.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com