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Apolactoferrin structure demonstrates ligand-induced conformational change in transferrins.
Deformation induces conformational change in the injection moulded samples.
No major conformational change in CD4 accompanies binding to ibalizumab.
Chen, Y., LeeH., Tong, H., Schwartz, M. & Zhu, C. Force regulated conformational change of integrin αVβ3.
A lack of conformational change was also noted upon HIF-1α peptide binding37.
A key question is how protein conformational change is coupled to substrate binding and release.
Figure 3: Binding of AZ to ODC induces global conformational change.
It induces dimerization by a conformational change in the ribosome 30S head-domains.
Instead, the paratope of the antibody undergoes a large conformational change to accommodate the epitope.
This conformational change is known to guide crystal growth in enamel formation25.
Activation of LOX requires a conformational change triggered by either osteopontin (OPN 40 and/or periostin41.
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