Sentence examples for conformational altered from inspiring English sources

Enlarged boutons in pro-aggregant mice contain conformational altered endogenous Tau (detected with MC1 antibody; Figure  3d and e), which was not observed in control littermates.

Regarding this hypothesis it is worthwhile of note that the binding of substrates to affinity sites located inside AcrB in Haemophilus influenzae induces noticeable conformational change altering the reactivity of specific residues [25].

Consequently, we think that phosphorylation on S66 might bring about a conformational change to alter BH3 domain availability, altering how Bid interacts with multidomain Bcl-2 proteins, and might explain a dominant-negative effect of nonfunctional Bid at the mitochondria.

The immobilized peptide undergoes a structural transition between α-helical and random coil conformation upon changes in pH and ionic concentration, but critically the threshold for conformational change is altered dramatically by molecular crowding within the peptide monolayer.

The light-induced conformational altering of PBsome was also found in UV-treated PBsome from which a PE fluorescence increase has been observed, arising from the disassembly of PBsome components [36].

It has been suggested that S100A8/S100A9 complex formation results in conformational change and altered biological function of the individual proteins [ 11, 38].

As one may have expected, different mutants showed different energy transfer ratios, consistent with conformational differences (altered distance and/or orientation of the fluorophores in the absence of substrate; Figure 4B).

A model based on a conformational change must alter calcium binding affinities to account for changes in calcium sensitivity.

These differences indicate that the linker region connecting the subdomain 2 and 3 is flexible and a conformational change can alter their relative orientations.

This conformational change could alter the binding of CRF1 antagonists, changing their efficacy in men versus women.

This result suggests a mechanism in which 14-3-3 14-3-3 14-3-3 and regulate key enzymes of TCA cycle through altering conformational change or scaffolding via proteinsprotein interaction.