Sentence examples for conformation target from inspiring English sources

Thus we may apply the law of mass-action to each of the binding reactions ai+A↔aiA, and obtain the equilibrium constant KiA = [ai][A]/[aiA]∼Zi ZA/ZiA, where Zi, ZA and ZiA are the single-particle partition functions of the i-th ligand conformation, target and complex, respectively.

Depending on access of novel CHT ligands to intracellular versus extracellular conformations, targeting CHT may afford labeling of activated cholinergic neurons where synaptic CHT density is elevated relative to less active states.

The Clp/Hsp100 ATPases are protein unfoldases that both alter protein conformation and target proteins for degradation.

Via promotion of the active GTP bound conformation of target GTPases, C3G has been implicated in the regulation of multiple cellular and developmental events including proliferation, differentiation and apoptosis.

Phosphorylation can alter the conformation of target proteins, resulting in activation or inactivation of function.

For further purification and conformation of target band, approximate amplified fragments were extracted from the corresponding polyacrylamide gel.

This study indicates alternative conformations and target sites to be used as basis for the design of novel inhibitor drugs.

Here, we report that TLQP-21 is intrinsically disordered and undergoes a disorder-to-order transition, adopting an α-helical conformation upon targeting cells expressing the C3aR1.

Dosage compensation mechanisms provide a paradigm to study the contribution of chromosomal conformation toward targeting and spreading of epigenetic regulators over a specific chromosome.

In summary we documented a novel active immunization approach using pABri in a β-sheet rich conformation that targets an abnormal conformation that is shared by aggregated/oligomeric Aβ and PHFs.

However for our study, we have to keep in mind that an 'abnormal' conformation was targeted, which might suggest a different way of action.