Sentence examples for conformation is required from inspiring English sources
Therefore, a resting state conformation is required for a comprehensive understanding on the overall cycle of conformational change.
All of the factors that hamper dimer formation alter the hydrogen-bonding arrangement that is key for forming the "closed loop" conformer of the monomeric protein, leading to the hypothesis that the closed conformation is required for dimer formation and may in fact lie at the dimer interface; NO binding stabilizes the "closed loop" conformation, with its hydrogen bonds.
On circular nucleosome arrays (Fig. 3 and Fig. 4), a major change in chromatin organization and/or nucleosome conformation is required to absorb the topological constraint confined within such clusters.
A shift to an open conformation is required for binding to the cytoskeleton.
In either case, a flexible or disordered conformation is required to enable degradation.
On the other hand, no major change of the conformation is required for the transformation.
This is consistent with the "closed loop" conformation being required for dimer formation, because this mutant protein does not dimerize.
The results provide direct support for the proposals that alternative straight-bridge-helix and bent-bridge-helix RNAP-active-center conformations exist and that cycling between straight-bridge-helix and bent-bridge-helix RNAP-active-center conformations is required for RNAP function.
Two alternate conformations are required to properly model the electron density for the aminopyridine and pyrrolidine rings.
Then new D-Ala and ATP substrates bind (with the enzyme still in its CoA-bound thiolation conformation), and CoA is released to allow the enzyme to adopt the adenylation conformation, which is required for ATP and D-Ala to react.
A higher degree of supercoiling favors the "folded" conformation, where the two stems stack onto the linear part of the chromosome, a conformation that is required for such processes as recombination and transposition.
