Sentence examples for conformation data from inspiring English sources

We observed effects on gene expression outside the CNV region, including apparent positional effects in cis and in trans at genomic segments with evidence of physical interaction in Hi-C chromosome conformation data.

The molecular design was performed to predict the binding mode of the most promising compounds 4, 10 and 12 with the active site of hCA IX, that showed appropriate fitting with the relevant amino acids in the binding pocket on the basis of standard bond lengths, angles, S score and E conformation data.

Recent analysis of genome-wide epigenetic modification data, mean replication timing (MRT) profiles and chromosome conformation data in mammals have provided increasing evidence that flexibility in replication origin usage is regulated locally by the epigenetic landscape and over larger genomic distances by the 3D chromatin architecture.

Series of MD conformation data was surveyed every 20 ps of all production runs.

Higher charge states (8+, 9+, and 10+) were also observed for this more expanded PagP conformation (data not shown).

A K2d program (Dichroweb) analysis performed on these peptide CD profiles confirmed that these peptides are largely in the random coil conformation (data not shown).

Also, no regular or rigid axial structure was required to reproduce the chromosome conformation capture data by simulation: simulating a more variable path of the loop array also reproduced the observed chromatin interaction data.

By modeling the chromatin structure using high-resolution chromosome conformation capture data and mapping the methylation level onto the modeled structure, we demonstrated that the patchiness of DNA methylation is related to chromatin structure.

Here we describe a computational module of the Integrative Modeling Platform (IMP, http://www.integrativemodeling.org) that uses chromosome conformation capture data to determine the 3D architecture of genomic domains and entire genomes at unprecedented resolutions.

Shape has been used to predict the 3D structure of over 400 bioactive oligosaccharides, ranging in size from disaccharides to tetradecasaccharides. Running on one single desktop machine it was possible to provide good conformation prediction data in less than one year for this library of compounds.

Our in situ hybridisation and chromosome conformation capture data support the hypothesis that enhancer 5F7 contributes to the expression pattern of OLIG genes in the posterior diencephalon but could also be regulating other more distant genes.