Sentence examples for confirming target from inspiring English sources

Furthermore, blocking the CD44 receptors present on the MiaPaCa-2 cells using free excess soluble HA prior to treatment with HA-PAMAM-CDF nano-formulation resulted in 1.71 fold increase in the IC50 value compared to non-targeted formulation (PAMAM-CDF), confirming target specificity of HA-PAMAM-CDF.

Interestingly, blocking the CD44 receptors on the cells using free excess soluble HA prior to incubation of cy3-labeled-siRNA loaded HA nano-assemblies resulted in >90% inhibition of the receptor mediated uptake, confirming target specificity.

Furthermore, YM-202074 administration showed significant blockade and displacement of [11C]ITDM in all investigated brain regions, confirming target engagement of mGluR1.

A dose-dependent increase in % RET was also observed confirming target tissue exposure.

In melting curve analysis, only one peak was observed confirming target specificity.

Primers used for RT-qPCR are described in Additional file 1: Table S1, and fragments were cloned and sequenced confirming target amplification.

Four days later, on May 14 , 2013 the Inspector General issued a report confirming targeting.

On May 10 , 2013 Ms. Lerner admitted targeting, calling it "absolutely incorrect, insensitive, and inappropriate". Four days later, on May 14 , 2013 the Inspector General issued a report confirming targeting.

Our model could be a valuable tool for confirming targets already described and for discovering new ones such as TOPK, a kinase involved in proliferation and motility.

Cholinergic DMnX cells could be double-stained with antibodies against the vesicular acetylcholine transporter and hα-syn, further confirming targeted transduction (Fig 1).

Compared to control shRNAscram, cells transfected with shRNAsat constructs displayed a significant decrease (∼70%) of the centromeric α-satellite transcript, confirming targeted destruction was accomplished.