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A similarity index was calculated between 31P-ZTE and CT skull images, confirming overall good co-localization (0.92 Dice index).
There were no significant differences between treatments in secondary outcome measures, confirming overall comparability in terms of efficacy and tolerability.
In addition to confirming overall gene expression patterns previously described for o2 mutants, we identified a number of other differences in mRNA transcript levels compared to wild type endosperms.
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Of the 32 patients refractory to both immunomodulators and proteasome inhibitors, confirmed overall response was achieved in 18 patients (56.3%; 95% CI 37.7 73.6).
A source with knowledge of intelligence confirmed: "Overall exercise of collection and analysis [is] done under a broad, overall legal authority which has to be renewed at intervals, and is signed off at a senior political level".
When a proposed change is relatively complex or when clinically relevant differences between the product before and after the change cannot be ruled out based on analytical studies, nonclinical and clinical bridging studies are generally required to confirm overall comparability.
Rev Paul Nicolson Taxpayers Against Poverty The same day that "David Cameron vows to create 3m apprenticeships" (Report, 20 October), repeating George Osborne's previous impossible pledge to the Tory conference, Alan Milburn's report on social mobility confirms overall apprentice starts are down and completion rates are falling.
The confirmed overall response rate was 50%; three patients with metastatic disease achieved complete responses.
Western blotting confirmed overall lower expression of Trp53 in SmoA1 +; Pten +/− mouse medulloblastomas (Data not shown).
The primary end point was confirmed overall response rate.
Random samples were scored manually in Adobe Photoshop, to confirm overall counting accuracy.
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CEO of Professional Science Editing for Scientists @ prosciediting.com