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Time to response (TTR) was recorded as the time from the date of commencing chemotherapy to demonstration of objective response assessed by independent review, and duration of response from the date of scan confirming objective response to disease progression.
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Confirmed objective response rate was 62%, with a complete response rate of 33% per immune-related response criteria.
It can be more suitable to confirm objective demands in system planning and energy trading, therefore being utilized in a wider range.
Findings from the acceptability survey confirm objective usage data.
The overall PSG results (after excluding sleep apnoea and PLMD) confirm objective sleep difficulties in patients with CFS.
Confirmed objective partial radiographic responses were observed in 5 % of patients receiving everolimus compared with 2%% of those receiving placebo.
Confirmed objective responses by RECIST criteria were seen in 8 out of 43 (19%) patients and stable disease for ⩾24 weeks in 9 out of 43 (21%) patients.
Confirmed objective tumor responses (all PRs) evaluated by investigator assessment were seen in 3 patients, corresponding to an ORR of 5%9595% CI, 1-13%, Table 3).
Confirmed objective responses were those for which a follow-up scan obtained at least four weeks later demonstrated the persistence of the response.
Depending on the number of objective responses observed on Schedule 4/2, sample size for the CDD cohort was determined using either a two-stage design (if ⩽5 confirmed objective responses were observed) or a single-stage design (if ⩾6 confirmed objective responses were observed).
It is likely that these results can be compared to those of other studies using sleep diaries, but objective measures, such as polysomnography or actigraphs, would be needed to confirm objective changes in sleep.
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