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All GFP-SEPT9 constructs were expressed in septin-like filamentous form, confirming functionality.
Importantly, expression of GFP::SPD-5 fully restored spindle assembly and embryonic viability, confirming functionality of the GFP fusion.
Figure 3B shows that neuronal SNAP-25 was efficiently cleaved by the chimera at concentrations in the low nanomolar range, confirming functionality of the assembled molecule.
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Simulation and experimental results have confirmed functionality of designed MEG.
To confirm functionality of the whole blood system we added PMA/Ionomycin which induced significant CD4 down-modulation (Fig. 4C).
Single-cell dynamic tracking in microfluidic systems was used to confirm functionality of the growth switches.
Tritiated thymidine incorporation by CTLL-2 and armadillo lymphoblasts confirmed functionality of the recombinant product.
The focus of this initial trial was system testing to confirm functionality and identify any necessary modifications or improvements.
We confirm functionality of identified eQTLs through their significant enrichment within open chromatin and highly deleterious SNPs, particularly at the exon level, suggesting substantial contribution of eQTLs to alternative splicing regulation.
To be clear, most of the leaks confirm functionality we already knew about, but now it's a case of being able to see how it works, rather than just hearing about the details from sources.
We further confirmed functionality of αq-CFP by evaluating its ability to support translocation of the βγ complex.
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