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Confirmatory biopsy of breast cancer metastases may have many potential benefits: confirming metastatic disease; disclosing non-malignant disease or other primary tumors; and confirming concordance (or discordance) of biological features of disease such as estrogen receptor (ER), progesterone receptor (PgR) and human epidermal growth factor receptor (HER 2 status.
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Internal Victorian Infectious Diseases Reference Laboratory validation confirmed concordance of results using these tests, and both produced highly reactive results in this case series.
All case files notified as clinically significant disease are reviewed by QTBCC clinicians to confirm concordance with ATS/IDSA criteria for disease (12 ).
41 In a validation study, a consultant paediatrician reviewed the records of the individuals with ASD to confirm concordance with the International Classification of Diseases (ICD) 10 criteria.
Second, the alignments between the sequenced BACs, P1-derived artificial chromosomes (PACs), pseudomolecules and the optical maps were manually examined to confirm concordance, and discordant regions were adjusted accordingly.
Supplementary Table 1 Primer Sequences for all 8 SNPs Using iPlex Chemistry on a MassARRAY Platform Supplementary Table 2 Results of Genotyping to Confirm Concordance Between Illumina and MassARRAY Technologies.
Availability of the concordance study with carefully defined sexual partnerships, application of MLST to confirm the concordance of samples between dyads and to identify unique strains, and use of full-length ompA sequences enabled us to identify ompA variants and compare and combine the results of the 2 strain typing methods.
Principal component analysis (PCA) of these 19 samples and 2 half-cell samples derived from the same cell further confirmed high concordance in two half-cell splits and the variability among single cells is higher, suggesting the existence of intercellular heterogeneity of miRNA expression (Supplementary Figure 5).
Previous study of common specimens confirmed complete concordance of PCR-SSP and oligonucleotide probe assays (n = 40).
Therefore, false deletions could be confirmed with concordance testing.
The dual verification exercise confirmed high concordance between the two independent data sources, SIR and Apollo.
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