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Forkhead box O (FoxO) 3a, as transcription factor, has been confirmed to modulate autophagic process.
Then a miRNA was predicted and confirmed to modulate the expression of UHRF1.
To analyze further the biological content of RNAi clones confirmed to modulate 128Q toxicity, we performed network-boosted data analysis.
The latter class of RNAi clones was subjected to a second screen in 128Q nematodes, which led to the identification of 664 RNAi clones confirmed to modulate neuronal dysfunction.
41 Another meta-analysis by Luckhaus and Sand indicated that ESR1 PvuII and XbaI polymorphisms were confirmed to modulate susceptibility to AD in Asian individuals, but not in Europeans.
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Since autophagy is involved in carcinogenesis, the ability of newly discovered or confirmed anticancer natural compounds to modulate this cellular pathway in PCa cells is receiving increasing attention, as supported by recent evidence.
To confirm the ability of nobiletin to modulate cyclic nucleotide signalling, the phosphorylation of VASP was assessed using phospho-specific antibodies upon stimulation with CRP-XL (1 μg·mL−1).
Moreover, we confirmed the capability of bcl-2 to modulate VEGF expression in several melanoma cells.
The screen yielded miRNAs belonging to the miR‐125 and miR‐181 families, and their ability to modulate CBX7 was confirmed in a number of ways (O'Loghlen et al., 2012).
These results therefore confirm our previous findings (Haeffner et al, 1997) concerning the ability of hGH to modulate the NF- κB-dependent pathway in response to various inducers.
The ability of aspirin to modulate MRP4 expression in MKs and to transfer it to platelets was confirmed in our in vivo studies.
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