After three consecutive rounds of panning, a screening ELISA was performed using the resulting enriched phage clones to confirm the presentation of specifically recognized salivary peptides.
Furthermore, we confirmed the processing and presentation on the surface of target mRNA-electroporated, HLA-transduced K562 cells for two peptides restricted to HLA-A3 and one to HLA-A11.
We confirmed the processing and presentation of HLA-A3-restricted T-cell epitopes from tyrosinase (TQYESGSMDK) and gp100 (LIYRRRLMK) and an HLA-A11-restricted T-cell epitope from gp100 (AVGATKVPR) via the cytolytic T-cell recognition of melanoma cell lines and/or K562 cells expressing the appropriate antigen and HLA molecule.
This result confirmed that the presentation of the active site of H2 relaxin is essentially unaffected by the tethering of the molecule to the PEG7 linker via the N-terminus of the B-chain.
Human mesenchymal stem cells seeded in the bilayer system differentiated into chondrocytes and osteoblasts in the respective layers, confirming the spatial presentation and prolonged activity of TGF-β1 and BMP-4.
Regular follow-up examinations at 3, 6, 9, and 12 months after initial presentation confirmed the pituitary lesion within the posterior lobe, while CT scans of thorax and abdomen remained negative except for the left-sided adrenal tumor.
Several presentations confirmed the clinical efficacy of the Herceptin (Genentech, San Francisco, CA, USA) antibody against the c-erbB2/HER2 cell-surface receptor when administered in combination with cytotoxics such as paclitaxel or vinorelbine.
Yet, there has been limited information in the area of quality of life research to confirm if the presentation ordering of composite measurement scales within a questionnaire would alter the results.
Results confirmed the superiority of the single-frame presentation.
In-vivo presentation assays using HspBP1 deficient transgenic mice confirmed the regulatory role of the CHIP-inhibitor in antigen presentation.
