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All results were manually checked and total 415 unique lipid structures were confirmed (Table 3; Additional file 2: Tables S2, S3, S4, and S5).
This prediction is confirmed (Table 2).
Even in our cellular system, based on the inclusion formation and cell viability, a distinct correlation was not confirmed (Table 1, Figure S7).
However, inclusion of literature information in the comparison revealed that approximately 42% of the edges found in the consensus network were confirmed (Table S1).
Seven out of eleven targets were confirmed with significant scores by both TargetScan and PITA, while three of them were only confirmed by PITA and one was not confirmed (Table 3).
The fact that ER QTL can be confirmed (Table 1), and that GR QTL are often cis-acting, both support the notion that our QTL list contains many true-positives.
If there are many such sites clustered in a region of DNA that indicate the same recipient (i.e. genome #2 is consistently the same, either Temecula-1 or M23), then recombination is confirmed (Table 3).
When the AIPC-cases with and without extrapancreatic biliary tract involvement (AIPC extrapancreatic and AIPC intrapancreatic, respectively) were considered separately, the results of the comparison of the entire AIPC group with CP and PSC were confirmed (Table 3).
Within each domain, the monophylies of most major divisions can be confirmed (Table 1) and is well supported by high robustness values (RP>80%, see Figure 2 and the corresponding color shadings that indicate various divisions).
Most cases were laboratory confirmed (Table 2).
Both exon 2 alleles have been independently confirmed (Table 1).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com