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Analysis of Nrf2 target genes confirmed induction was taking place by an oxidative stress response (S3).
Analysis of additional potential gene expression differences that might exist between liver and SI following PEITC administration confirmed induction of the Cyp2b10 gene and protein expression in both tissues (Fig. 2), an observation that implicates a role for CAR in the induction process.
We also confirmed induction of phosphorylated eIF2α upon treatment with NSC-652287 (Fig. 7d).
Recent vaccine trials utilizing Adenovirus based vaccines expressing HIV antigens confirmed induction of cellular immune responses, but these responses failed to prevent HIV infections in vaccinees.
A more detailed comparison of KG1a and HL60 cells confirmed induction of annexin-V labelling (Figure 2E) together with uptake of propidium iodide (PI), consistent with apoptosis in KG1a cells but not in HL60 cells (Figure 2E and 2F).
Cell cycle analysis using 7-AAD staining on SHG-MM5 and SGH-MM6 cell confirmed induction of MM cell death by CD137 ligand signaling as evidenced by the increase in hypodiploid DNA sub-G1/debris sub-G1/debrisre 2C).
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Protein expression paralleled the findings of gene expression, with Western blots confirming induction of UGT1A1 and CYP2B10 in liver and SI.
This question is related to the link that Quine draws between kinds and what it is that confirms induction.
These findings confirms induction of TLR6 transcript, protein and function by ambient hypoxia.
In addition, no means were employed to confirm induction of hydrocephalus before antioxidant treatment began.
To further confirm induction of apoptosis by SNW1 knockdown, we examined the expression of cleaved PARP.
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