Sentence examples for confirmed functionally from inspiring English sources
Infusion placement was confirmed functionally in later tests by reversible inactivation of the MD via intra-MD infusion of tetrodotoxin (TTX; 10 ng/side), and subsequently by direct histological examination.
The homology of the bacterial protein was confirmed functionally by DNA-binding assays.
Two putative caspase recognition and cleavage sites, each containing the ExD sequence [13], [29] [31], were identified in silico and then confirmed functionally in human BAG3.
All mutants were confirmed functionally active in a liposome-based F− efflux assay.
Each of these mutations are novel missense mutations, which are highly predicted to be deleterious, although this has not been confirmed functionally.
While genome-wide association studies in human and quantitative trait loci mapping in mice have provided evidence for multiple susceptibility genes, few of these have been confirmed functionally.
Therefore, these results altogether confirm functionally that p110α/p85β and p110α/p55γ are the largely predominant PI3-K isoform complexes in HIEC cells, in addition to indicating that both complexes contribute in the activation of Akt-1 and a consequent promotion/maintenance of survival in these cells.
For a comparative structural model of peptidase HtrA from Helicobacter pylori, we performed mutation studies for predicted hot-spot residues, which were confirmed as functionally relevant for HtrA activity or oligomerization.
Interestingly, N. aberrans-specific candidate GH enzymes were also identified, although these remain to be confirmed and functionally characterized.
Most current published information on PcG phosphorylation neither unequivocally identifies responsible kinases nor targeted amino acid residues, and the majority of existing in vitro data will have to be confirmed and functionally tested in vivo.
Specifically, inhibition of the constitutive activation of PI3K/Akt pathway substantially suppressed Cx26 expression, and Cx26 was confirmed to functionally interplay with PI3K/Akt signaling to promote EMT and gefitinib resistance in NSCLC cells.
