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This study highlights the morphology of lens opacities in a family with genetically confirmed disease.
A spatial model of disease occurrence was developed, using data from an outbreak of serologically confirmed disease in an unvaccinated population of horses at 108 locations in northern Indiana between 3 August and 17 October 2002.
To determine whether asymptomatic persons with biochemical evidence of very long-chain acyl-CoA dehydrogenase (VLCAD) deficiency identified through expanded newborn screening with tandem mass spectometry have confirmed disease.
In two patients without visually detectable activity on 90Y PET/CT within targeted tumor vascular thrombosis, follow-up scans confirmed disease progression in these lesions (Figure 4).
Cases were unclassifiable if they did not meet criteria for laboratory confirmed disease, and either had no household contacts, or contacts without laboratory confirmed disease.
We could only study patients from one centre, with bacteriologically confirmed disease, in whom multiple serial CSF specimens were available.
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We have confirmed disease-enriched profiles for several of these candidates in sera collected from patients with early-stage disease.
The candidate-gene approach has brought some success; however, the overall yield of confirmed disease-susceptibility genes gathered by this approach has been limited.
Culture-confirmed disease was present in 28 of 55 (53%) children younger than 5 years, 7 of 10 (70%) children 5 to 15 years, and 40 of 49 (82%) contacts older than 15 years.
Abnormal findings by chest radiograph were associated with probable/culture-confirmed disease in this cohort.
Thirty patients with culture-confirmed disease were female, and 27 were male.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com