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Because the new findings were based on a follow-up of the first year that lithotripsy was used at the Mayo Clinic, in 1985, confirmatory studies from other medical centers are needed, Dr. Krambeck said.
Particularly, confirmatory studies using the same methodology are often lacking.
Further confirmatory studies may be necessary to prove the causal relationships.
However, proper preclinical work and stringent validation are needed before taking forward biomarkers into confirmatory studies.
Additionally, a recent study has identified discrepant results regarding its diagnostic performance [2] suggesting confirmatory studies to be required.
Some of these factors are not ordinarily monitored or studied in the literature, and confirmatory studies are therefore not performed.
Confirmatory studies revealed that the protein yield under optimum conditions was 80.71 g/100 g seed meal.
Nevertheless some confirmatory studies must be considered to foster the use of anti-EGFR therapies including safety and clinical use.
Thus, confirmatory studies with large sample sizes are required to validate this study.
First, confirmatory studies with large sample sizes are required to validate this study.
The surface exposure of our OmpL proteins shown by surface IFA prompted us to perform additional, confirmatory studies.
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