Nevertheless, a formal confirmation of iNOS function in skeletal muscle awaits the generation of an animal model of skeletal muscle-specific knockout of the iNos gene.
It should be pointed out that the HCS screen was performed independently of our profiling study and thus provided an unbiased confirmation of the function of these genes that were identified as putative miRNA targets.
Future work will be aimed at a confirmation of the function and kinetic properties of VSFP3.1 in differentiated neurons, an important step towards realization of an optical sensor of neuronal circuit activity.
The significance of this classification with respect to our proposed role of ROS-bZIP1 is unclear at this point but can be explained with better understanding or confirmation of the function of ROS-bZIP1 during chilling stress.
The confirmation of FOXP3 function derives from a recent discover: a mutation of the FOXP3 gene may lead to a pediatric syndrome characterized by the association of several different autoimmune diseases (IPEX Syndrome: immune dysfunction, poliendocrinopathy, enteropathy, and X-linked) [ 9].
Genetic analysis of parasite mutants has been critical for the analysis and confirmation of gene function in Leishmania species (e.g. Spath et al., 2003; Ortiz et al., 2007).
The tyrosine pathway is responsible for the synthesis of L-DOPA and dopamine, which are precursors to NADA, thus demonstrating a logical confirmation of biological function recovered from correlational data.
Bioinformatics analysis together with reverse genetics studies are especially helpful to pinpoint the genes involved in secondary cell wall formation [ 50], and the present confirmation of the function of MtIRX1 highlights the potential of the present dataset for further cell wall gene discovery.
The goals analysis had three aims in supplementing the findings of the systematic review: (1) identification of new items by patients and carers, (2) confirmation of passive function items identified in the systematic review and (3) ensuring that items relevant to the proximal upper limb are considered for inclusion.
There are three kinds of test case confirmation targets after applying a patch; one is a confirmation of normal functioning, one is a data normality confirmation, and the other is a confirmation of performance.
The two criteria for a crop to perform genome editing are the accessibility of genomic data and confirmation of gene functions as well as the availability for the platform of genetic transformation and regeneration process.
