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The feasibility of stable internal free surfaces is confirmed by CFD simulations, however an experimental confirmation is mandatory.
Histologic confirmation is mandatory, followed by further diagnostic assessments with regard to other organ involvement.
However, since molecular methods do not distinguish between live and death bacteria, culture confirmation is mandatory.
Outside the United States, in addition to the above methods, many countries have national cancer registries where reporting of all incident malignancies to a central database with confirmation is mandatory.
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Therefore, histologic confirmation with biopsy is mandatory [9, 11, 12].
However, as it is difficult to conclusively demonstrate receptor targeting in vitro, in vivo confirmation of targeting is mandatory and animal experiments with AEZS-125 in TNBC are already underway.
Diagnostic imaging plays an important role in the management of patients with hepatocellular carcinoma (HCC) since pathology confirmation is not mandatory for definitive diagnosis.
A histologic specimen for confirmation of amyloid deposits is mandatory for an accurate diagnosis.
The central confirmation of histopathological diagnoses is mandatory to include patients into the outlined study.
Confirmation of the infection is mandatory and must be achieved by isolation and characterization of the pathogen.
For confirmation, analysis by instrumental techniques is mandatory.
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