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10 This requires confirmation by two consecutive samples.
All complete and partial responses required confirmation by two consecutive observations no less than 4 weeks apart.
Sustained biomarker decline (i.e. confirmation by two measurements spaced at least 28 days apart) was not required.
Information regarding family history of obesity was obtained by drawing three-generation pedigrees and confirmation by two independent sources.
We did not require a sustained biomarker decline (i.e. confirmation by two measurements spaced at least 28 days apart) for this analysis.
Where discrepancies arose between the staining of cores from the same tumor, an average of the scores was taken, with confirmation by two observers using a double-headed microscope with a consensus decision taken in all cases.
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Further replicating loci in this French study (EXT2-ALX4 and LOC387761) have not met confirmation by the four subsequent scans.
Nine genic CNVRs found in C57BL/6 J mice were selected for CNV confirmation by ddPCR in five C57BL/6 J, five CBA/CaJ and four DBA/2 J inbred mice (see Additional file 1: Table S7).
Sections (4 μm) were cut for immunohistochemical analysis and histopathological confirmation of diagnosis by two pathologists (EB, JCC).
As suggested by the metaphor of triangulation, the confirmation of findings by two or more independent measurement processes greatly enhances confidence in the research findings [ 41].
Histology of the core needle biopsies provided definitive diagnoses of histiocytic sarcoma in ten dogs, including confirmation by immunohistochemistry in six dogs.
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